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Exploring Relationships between the Density of Charged Tracts within Disordered Regions and Phase Separation

Biomolecular condensates form through a process termed phase separation and play diverse roles throughout the cell. Proteins that undergo phase separation often have disordered regions that can engage in weak, multivalent interactions; however, our understanding of the sequence grammar that defines...

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Détails bibliographiques
Publié dans:Pac Symp Biocomput
Auteurs principaux: Somjee, Ramiz, Mitrea, Diana M., Kriwacki, Richard W.
Format: Artigo
Langue:Inglês
Publié: 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939312/
https://ncbi.nlm.nih.gov/pubmed/31797598
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