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Chromatin conformation analysis of primary patient tissue using a low input Hi-C method

Chromatin conformation constitutes a fundamental level of eukaryotic genome regulation. However, our ability to examine its biological function and role in disease is limited by the large amounts of starting material required to perform current experimental approaches. Here, we present Low-C, a Hi-C...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Díaz, Noelia, Kruse, Kai, Erdmann, Tabea, Staiger, Annette M., Ott, German, Lenz, Georg, Vaquerizas, Juan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265268/
https://ncbi.nlm.nih.gov/pubmed/30498195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06961-0
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