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Generation of Genome-wide Chromatin Conformation Capture Libraries from Tightly Staged Early Drosophila Embryos

Investigating the three-dimensional architecture of chromatin offers invaluable insight into the mechanisms of gene regulation. Here, we describe a protocol for performing the chromatin conformation capture technique in situ Hi-C on staged Drosophila melanogaster embryo populations. The result is a...

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Bibliografische gegevens
Gepubliceerd in:J Vis Exp
Hoofdauteurs: Hug, Clemens B., Vaquerizas, Juan M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6235413/
https://ncbi.nlm.nih.gov/pubmed/30346395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/57001
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