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Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning

The relationship between chromatin organization and gene regulation remains unclear. While disruption of chromatin domains and domain boundaries can lead to misexpression of developmental genes, acute depletion of regulators of genome organization has a relatively small effect on gene expression. It...

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Bibliografiske detaljer
Udgivet i:Nat Genet
Main Authors: Ing-Simmons, Elizabeth, Vaid, Roshan, Bing, Xin Yang, Levine, Michael, Mannervik, Mattias, Vaquerizas, Juan M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group US 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8035076/
https://ncbi.nlm.nih.gov/pubmed/33795866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-021-00799-x
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