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Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines
BACKGROUND: Sequencing of patient-derived xenograft (PDX) mouse models allows investigation of the molecular mechanisms of human tumor samples engrafted in a mouse host. Thus, both human and mouse genetic material is sequenced. Several methods have been developed to remove mouse sequencing reads fro...
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| Udgivet i: | Gigascience |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8058593/ https://ncbi.nlm.nih.gov/pubmed/33880552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giab022 |
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