Chromatin conformation capture (Hi-C) sequencing of patient-derived xenografts: analysis guidelines

BACKGROUND: Sequencing of patient-derived xenograft (PDX) mouse models allows investigation of the molecular mechanisms of human tumor samples engrafted in a mouse host. Thus, both human and mouse genetic material is sequenced. Several methods have been developed to remove mouse sequencing reads fro...

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Библиографические подробности
Опубликовано в: :Gigascience
Главные авторы: Dozmorov, Mikhail G, Tyc, Katarzyna M, Sheffield, Nathan C, Boyd, David C, Olex, Amy L, Reed, Jason, Harrell, J Chuck
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2021
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8058593/
https://ncbi.nlm.nih.gov/pubmed/33880552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giab022
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