Synthesis and In Vitro Antiproliferative Activity of Novel Androst-5-ene Triazolyl and Tetrazolyl Derivatives

A straightforward and reliable method for the regioselective synthesis of steroidal 1,4-disubstituted triazoles and 1,5-disubstituted tetrazoles via copper(I)-catalyzed cycloadditions is reported. Heterocycle moieties were efficiently introduced onto the starting azide compound 3β-acetoxy-16β-azidom...

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Vydáno v:Molecules
Hlavní autoři: Kádár, Zalán, Kovács, Dóra, Frank, Éva, Schneider, Gyula, Huber, Judit, Zupkó, István, Bartók, Tibor, Wölfling, János
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264172/
https://ncbi.nlm.nih.gov/pubmed/21659965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16064786
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