A molecular understanding of d-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells

2-Methoxyestradiol (ME), one of the most widely investigated A-ring-modified metabolites of estrone, exerts significant anticancer activity on numerous cancer cell lines. Its pharmacological actions, including cell cycle arrest, microtubule disruption and pro-apoptotic activity, have already been de...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Minorics, Renáta, Bózsity, Noémi, Molnár, Judit, Wölfling, János, Mernyák, Erzsébet, Schneider, Gyula, Ocsovszki, Imre, Zupkó, István
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4594678/
https://ncbi.nlm.nih.gov/pubmed/26228523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12587
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