Synthesis and Biological Evaluation of Triazolyl 13α-Estrone–Nucleoside Bioconjugates

2′-Deoxynucleoside conjugates of 13α-estrone were synthesized by applying the copper-catalyzed alkyne–azide click reaction (CuAAC). For the introduction of the azido group the 5′-position of the nucleosides and a propargyl ether functional group on the 3-hydroxy group of 13α-estrone were chosen. The...

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Bibliografische gegevens
Gepubliceerd in:Molecules
Hoofdauteurs: Bodnár, Brigitta, Mernyák, Erzsébet, Wölfling, János, Schneider, Gyula, Herman, Bianka Edina, Szécsi, Mihály, Sinka, Izabella, Zupkó, István, Kupihár, Zoltán, Kovács, Lajos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6273310/
https://ncbi.nlm.nih.gov/pubmed/27626395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21091212
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