Targeted Sequencing Identifies Missense variant in the BEST3 gene associated with Antihypertensive Response to Hydrochlorothiazide

Chromosome 12q15 was identified in Genetic Epidemiology of Response Assessment (GERA) and replicated in Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) for its association with blood pressure (BP) response to hydrochlorothiazide (HCTZ). However, the functional variant is unknown and...

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Detalhes bibliográficos
Publicado no:Pharmacogenet Genomics
Main Authors: Singh, Sonal, Wang, Zhiying, Shahin, Mohamed, Langaee, Taimour Y., Gong, Yan, Turner, Stephen T., Chapman, Arlene B., Gums, John G., McDonough, Caitrin W., Bailey, Kent R., Beitelshees, Amber L, Cooper-DeHoff, Rhonda M., Scherer, Steve, Boerwinkle, Eric, Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262886/
https://ncbi.nlm.nih.gov/pubmed/30289819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000353
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