Hydrochlorothiazide-induced hyperuricaemia in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study

OBJECTIVE: Elevations in uric acid (UA) and the associated hyperuricaemia are commonly observed secondary to treatment with thiazide diuretics. We sought to identify novel single-nucleotide polymorphisms (SNPs) associated with hydrochlorothiazide (HCTZ)-induced elevations in UA and hyperuricaemia. M...

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Detalhes bibliográficos
Main Authors: Vandell, Alexander G., McDonough, Caitrin W., Gong, Yan, Langaee, Taimour Y., Lucas, Anne M., Chapman, Arlene B., Gums, John G., Beitelshees, Amber L., Bailey, Kent R., Johnson, Richard J., Boerwinkle, Eric, Turner, Stephen T., Cooper-DeHoff, Rhonda M., Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130802/
https://ncbi.nlm.nih.gov/pubmed/24612202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12215
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