Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies

β-blockers show variable efficacy as antihypertensives. Herein, we evaluated plasma miRNAs as biomarkers for defining antihypertensive response to β-blockers. Expression of 22 β-blocker pharmacodynamics-related miRNAs was assessed in baseline plasma samples from 30 responders and 30 non-responders t...

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Publicado en:Eur J Pharm Sci
Main Authors: Solayman, Mohamed H., Langaee, Taimour Y., Gong, Yan, Shahin, Mohamed H., Turner, Stephen T., Chapman, Arlene B., Gums, John G., Boerwinkle, Eric, Beitelshees, Amber L., El-Hamamsy, Manal, El-Wakeel, Lamia, Cooper-DeHoff, Rhonda M., Badary, Osama A., Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467266/
https://ncbi.nlm.nih.gov/pubmed/30753892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejps.2019.02.013
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