Pharmacogenomics of Antihypertensive drugs: Rationale and Design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study

BACKGROUND: Selection of antihypertensive therapy is often empiric and use of genetic information to guide drug therapy selection holds future promise. TRIAL DESIGN: The objective of this trial is to identify the genetic determinants of the antihypertensive and adverse metabolic responses to a thiaz...

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Autori principali: Johnson, Julie A., Boerwinkle, Eric, Zineh, Issam, Chapman, Arlene B., Bailey, Kent, Cooper-DeHoff, Rhonda M., Gums, John, Curry, R. Whit, Gong, Yan, Beitelshees, Amber L., Schwartz, Gary, Turner, Stephen T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671287/
https://ncbi.nlm.nih.gov/pubmed/19249413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ahj.2008.11.018
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