Association of Chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression

A recent genome-wide analysis discovered an association between a haplotype (from rs317689/rs315135/rs7297610) on Chromosome 12q15 and blood pressure response to hydrochlorothiazide in African-Americans. Our aim was to replicate this association and investigate possible functional mechanisms. We obs...

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Detalhes bibliográficos
Main Authors: Duarte, Julio D., Turner, Stephen T., Tran, BaoAnh, Chapman, Arlene B., Bailey, Kent R., Gong, Yan, Gums, John G., Langaee, Taimour Y., Beitelshees, Amber L., Cooper-Dehoff, Rhonda M., Boerwinkle, Eric, Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360116/
https://ncbi.nlm.nih.gov/pubmed/22350108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2012.4
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