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ACTION OF NUCLEOSIDES AND NUCLEOTIDES AT 7 TRANSMEMBRANE-SPANNING RECEPTORS

Ribose ring-constrained nucleosides and nucleotides to act at cell-surface purine recesptors have been designed and synthesized. At the P2Y(1) nucleotide receptor and the A(3) adenosine receptor (AR) the North envelope conformation of ribose is highly preferred. We have applied mutagenesis and rhodo...

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Detalles Bibliográficos
Publicado en:Nucleosides Nucleotides Nucleic Acids
Main Authors: Jacobson, Kenneth A., Costanzi, Stefano, Kim, Soo-Kyung, Roh, Eunjoo, Joshi, Bhalchandra V., Tchilibon, Susanna, Duong, Heng T., Gao, Zhan-Guo
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262823/
https://ncbi.nlm.nih.gov/pubmed/17067963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770600919027
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