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Stabilization of the p53-DNA complex by the nuclear protein Dmp1α

We recently reported the existence of a physical interaction between the Myb-like transcription factor Dmp1 (Dmtf1) and p53 in which Dmp1 antagonized polyubiquitination of p53 by Mdm2 and promoted its nuclear localization. Dmp1 significantly stabilized p53-DNA complexes on promoters that contained p...

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Detalhes bibliográficos
Publicado no:Cancer Invest
Main Authors: Kendig, Robert D., Kai, Fumitake, Fry, Elizabeth A., Inoue, Kazushi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262109/
https://ncbi.nlm.nih.gov/pubmed/28406729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07357907.2017.1303505
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