Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation

Patients with diabetes mellitus (DM) are at high risk for cognitive dysfunction. Endoplasmic reticulum stress (ERS) and inflammation play crucial roles in DM. Gastrodin (Gas), the main component of Gastrodia elata, possesses anti-oxidative stress, anti-inflammatory, and neuroprotective effects. This...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Ye, Tianyuan, Meng, Xiangbao, Zhai, Yadong, Xie, Weijie, Wang, Ruiying, Sun, Guibo, Sun, Xiaobo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262084/
https://ncbi.nlm.nih.gov/pubmed/30524286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01346
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