Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation

Patients with diabetes mellitus (DM) are at high risk for cognitive dysfunction. Endoplasmic reticulum stress (ERS) and inflammation play crucial roles in DM. Gastrodin (Gas), the main component of Gastrodia elata, possesses anti-oxidative stress, anti-inflammatory, and neuroprotective effects. This...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ye, Tianyuan, Meng, Xiangbao, Zhai, Yadong, Xie, Weijie, Wang, Ruiying, Sun, Guibo, Sun, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262084/
https://ncbi.nlm.nih.gov/pubmed/30524286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01346
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