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Notoginsenoside R1 ameliorates diabetic encephalopathy by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

Numerous researches supported that oxidative stress and inflammation play important roles in the development of diabetic encephalopathy (DEP). Notoginsenoside R1 (NGR1), one major component of Panax notoginseng, is believed to have anti-oxidative, anti-inflammatory and neuroprotective properties. Ho...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhai, Yadong, Meng, Xiangbao, Luo, Yun, Wu, Yongmei, Ye, Tianyuan, Zhou, Ping, Ding, Shilan, Wang, Min, Lu, Senbao, Zhu, Lili, Sun, Guibo, Sun, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823646/
https://ncbi.nlm.nih.gov/pubmed/29507694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24295
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