The Roles of Endoplasmic Reticulum in NLRP3 Inflammasome Activation

The NLRP3 (nucleotide-binding domain, leucine-rich-repeat-containing family, pyrin domain-containing 3) inflammasome senses pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs), and activates caspase-1, which provokes release of proinflammatory cytokines su...

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Bibliographic Details
Main Authors: Yang Zhou, Zhizi Tong, Songhong Jiang, Wenyan Zheng, Jianjun Zhao, Xiangmei Zhou
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
endoplasmic reticulum
NLRP3
inflammasome
IRE1α
Online Access:https://www.mdpi.com/2073-4409/9/5/1219
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