Synergistic interaction between the agonism of cebranopadol at nociceptin/orphanin FQ and classical opioid receptors in the rat spinal nerve ligation model

Cebranopadol (trans‐6′‐fluoro‐4′,9′‐dihydro‐N,N‐dimethyl‐4‐phenyl‐spiro[cyclohexane‐1,1′(3′H)‐pyrano[3,4‐b]indol]‐4‐amine) is a novel analgesic nociceptin/orphanin FQ opioid peptide (NOP) and classical opioid receptor (MOP, DOP, and KOP) agonist with highly efficacious and potent activity in a broad...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Christoph, Thomas, Raffa, Robert, De Vry, Jean, Schröder, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262002/
https://ncbi.nlm.nih.gov/pubmed/30519474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.444
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