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A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

Lysine methylation is a key regulator of histone protein function. Beyond histones, few connections have been made to the enzymes responsible for the deposition of these posttranslational modifications. Here, we debut a high-throughput functional proteomics platform that maps the sequence determinan...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Adv
Κύριοι συγγραφείς: Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Association for the Advancement of Science 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261651/
https://ncbi.nlm.nih.gov/pubmed/30498785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav2623
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