A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

Lysine methylation is a key regulator of histone protein function. Beyond histones, few connections have been made to the enzymes responsible for the deposition of these posttranslational modifications. Here, we debut a high-throughput functional proteomics platform that maps the sequence determinan...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2018
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261651/
https://ncbi.nlm.nih.gov/pubmed/30498785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav2623
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