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A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity

Lysine methylation is a key regulator of histone protein function. Beyond histones, few connections have been made to the enzymes responsible for the deposition of these posttranslational modifications. Here, we debut a high-throughput functional proteomics platform that maps the sequence determinan...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Adv
मुख्य लेखकों: Cornett, Evan M., Dickson, Bradley M., Krajewski, Krzysztof, Spellmon, Nicholas, Umstead, Andrew, Vaughan, Robert M., Shaw, Kevin M., Versluis, Philip P., Cowles, Martis W., Brunzelle, Joseph, Yang, Zhe, Vega, Irving E., Sun, Zu-Wen, Rothbart, Scott B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Association for the Advancement of Science 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261651/
https://ncbi.nlm.nih.gov/pubmed/30498785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav2623
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