SIRT1 deacetylase in aging‐induced neuromuscular degeneration and amyotrophic lateral sclerosis

SIRT1 is an NAD(+)‐dependent deacetylase that functions in a variety of cells and tissues to mitigate age‐associated diseases. However, it remains unknown if SIRT1 also acts to prevent pathological changes that accrue in motor neurons during aging and amyotrophic lateral sclerosis (ALS). In this stu...

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Xehetasun bibliografikoak
Argitaratua izan da:Aging Cell
Egile Nagusiak: Herskovits, Adrianna Z., Hunter, Tegan A., Maxwell, Nicholas, Pereira, Katherine, Whittaker, Charles A., Valdez, Gregorio, Guarente, Leonard P.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2018
Gaiak:
Original Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260920/
https://ncbi.nlm.nih.gov/pubmed/30295421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12839
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