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SIRT1 deacetylase in aging‐induced neuromuscular degeneration and amyotrophic lateral sclerosis
SIRT1 is an NAD(+)‐dependent deacetylase that functions in a variety of cells and tissues to mitigate age‐associated diseases. However, it remains unknown if SIRT1 also acts to prevent pathological changes that accrue in motor neurons during aging and amyotrophic lateral sclerosis (ALS). In this stu...
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| Publié dans: | Aging Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6260920/ https://ncbi.nlm.nih.gov/pubmed/30295421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12839 |
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