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The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motoneurons and degradation of the neuromuscular junctions (NMJ). Consistent with the dying-back hypothesis of motoneuron degeneration the decline in synaptic function initiates from the presynaptic terminals in ALS. Oxi...

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Detaylı Bibliyografya
Asıl Yazarlar: Pollari, Eveliina, Goldsteins, Gundars, Bart, Geneviève, Koistinaho, Jari, Giniatullin, Rashid
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026683/
https://ncbi.nlm.nih.gov/pubmed/24860432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00131
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