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The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motoneurons and degradation of the neuromuscular junctions (NMJ). Consistent with the dying-back hypothesis of motoneuron degeneration the decline in synaptic function initiates from the presynaptic terminals in ALS. Oxi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4026683/ https://ncbi.nlm.nih.gov/pubmed/24860432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00131 |
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