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ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase

Accumulation of proteins in aberrant conformation occurs in many neurodegenerative diseases. Furthermore, dysfunctions in protein handling in endoplasmic reticulum (ER) and the following ER stress have been implicated in a vast number of diseases, such as amyotrophic lateral sclerosis (ALS). During...

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Bibliografske podrobnosti
izdano v:Front Cell Neurosci
Main Authors: Jaronen, Merja, Goldsteins, Gundars, Koistinaho, Jari
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4251436/
https://ncbi.nlm.nih.gov/pubmed/25520620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00402
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