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ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase
Accumulation of proteins in aberrant conformation occurs in many neurodegenerative diseases. Furthermore, dysfunctions in protein handling in endoplasmic reticulum (ER) and the following ER stress have been implicated in a vast number of diseases, such as amyotrophic lateral sclerosis (ALS). During...
Shranjeno v:
izdano v: | Front Cell Neurosci |
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Main Authors: | , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Frontiers Media S.A.
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4251436/ https://ncbi.nlm.nih.gov/pubmed/25520620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00402 |
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