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Mechanisms of Neuroprotection by Protein Disulphide Isomerase in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterised by the progressive loss of motor neurons, leading to paralysis and death within several years of onset. Although protein misfolding is a key feature of ALS, the upstream triggers of disease remain elusive. R...

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Detalhes bibliográficos
Main Authors: Walker, Adam K., Atkin, Julie D.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096316/
https://ncbi.nlm.nih.gov/pubmed/21603027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/317340
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