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IL-33 suppresses GSK-3β activation through an ST2-independent MyD88/TRAF6/RIP/PI3K/Akt pathway

AIMS: The present study was conducted to explore the effect of interleukin-33 (IL-33) on glycogen synthase kinase-3β (GSK-3β) activation involving Tau phosphorylation, a critical causative factor for Alzheimer's disease (AD). MAIN METHODS: Experiments were performed using PC-12 cells. Target pr...

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Detalhes bibliográficos
Publicado no:Heliyon
Autor principal: Nishizaki, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260469/
https://ncbi.nlm.nih.gov/pubmed/30533546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e00971
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