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Deletion of FADD in Macrophages and Granulocytes Results in RIP3- and MyD88-Dependent Systemic Inflammation

Myeloid cells, which include monocytes, macrophages, and granulocytes, are important innate immune cells, but the mechanism and downstream effect of their cell death on the immune system is not completely clear. Necroptosis is an alternate form of cell death that can be triggered when death receptor...

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Publicado en:PLoS One
Main Authors: Schock, Suruchi N., Young, Jennifer A., He, Tina H., Sun, Yuefang, Winoto, Astar
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395384/
https://ncbi.nlm.nih.gov/pubmed/25874713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124391
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