Enhancement of Pneumocandin B(0) Production in Glarea lozoyensis by Low-Temperature Adaptive Laboratory Evolution

The production of pneumocandin B(0) is limited by feedback inhibition. Here, low-temperature adaptive laboratory evolution (ALE) was used to improve the production capacity of Glarea lozoyensis by enhancing its membrane permeability. After 50 cycles of ALE, the pneumocandin B(0) production of the en...

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Détails bibliographiques
Publié dans:Front Microbiol
Auteurs principaux: Song, Ping, Zhang, Ke, Zhang, Sen, Huang, Bao-Qi, Ji, Xiao-Jun, Ren, Lu-Jing, Gao, Song, Wen, Jian-Ping, Huang, He
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Microbiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259640/
https://ncbi.nlm.nih.gov/pubmed/30519220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02788
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