Enhancement of Pneumocandin B(0) Production in Glarea lozoyensis by Low-Temperature Adaptive Laboratory Evolution

The production of pneumocandin B(0) is limited by feedback inhibition. Here, low-temperature adaptive laboratory evolution (ALE) was used to improve the production capacity of Glarea lozoyensis by enhancing its membrane permeability. After 50 cycles of ALE, the pneumocandin B(0) production of the en...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Song, Ping, Zhang, Ke, Zhang, Sen, Huang, Bao-Qi, Ji, Xiao-Jun, Ren, Lu-Jing, Gao, Song, Wen, Jian-Ping, Huang, He
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259640/
https://ncbi.nlm.nih.gov/pubmed/30519220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.02788
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