Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease

The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra (SN), the main structure affected in Parkinson’s di...

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Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Tayara, Khadija, Espinosa-Oliva, Ana M., García-Domínguez, Irene, Ismaiel, Afrah Abdul, Boza-Serrano, Antonio, Deierborg, Tomas, Machado, Alberto, Herrera, Antonio J., Venero, José L., de Pablos, Rocío M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258993/
https://ncbi.nlm.nih.gov/pubmed/30519161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00440
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