Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease

The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra (SN), the main structure affected in Parkinson’s di...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Cell Neurosci
Päätekijät: Tayara, Khadija, Espinosa-Oliva, Ana M., García-Domínguez, Irene, Ismaiel, Afrah Abdul, Boza-Serrano, Antonio, Deierborg, Tomas, Machado, Alberto, Herrera, Antonio J., Venero, José L., de Pablos, Rocío M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018
Aiheet:
Neuroscience
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258993/
https://ncbi.nlm.nih.gov/pubmed/30519161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00440
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