Divergent Effects of Metformin on an Inflammatory Model of Parkinson’s Disease

The oral antidiabetic drug metformin is known to exhibit anti-inflammatory properties through activation of AMP kinase, thus protecting various brain tissues as cortical neurons, for example. However, the effect of metformin on the substantia nigra (SN), the main structure affected in Parkinson’s di...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Tayara, Khadija, Espinosa-Oliva, Ana M., García-Domínguez, Irene, Ismaiel, Afrah Abdul, Boza-Serrano, Antonio, Deierborg, Tomas, Machado, Alberto, Herrera, Antonio J., Venero, José L., de Pablos, Rocío M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258993/
https://ncbi.nlm.nih.gov/pubmed/30519161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00440
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