Herpes Simplex Virus 1 Latency and the Kinetics of Reactivation Are Regulated by a Complex Network of Interactions between the Herpesvirus Entry Mediator, Its Ligands (gD, BTLA, LIGHT, and CD160), and the Latency-Associated Transcript

Recently, we reported that the herpesvirus entry mediator (HVEM; also called TNFRSF14 or CD270) is upregulated by the latency-associated transcript (LAT) of herpes simplex virus 1 (HSV-1) and that the absence of HVEM affects latency reactivation but not primary infection in ocularly infected mice. g...

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Vydáno v:J Virol
Hlavní autoři: Wang, Shaohui, Ljubimov, Alexander V., Jin, Ling, Pfeffer, Klaus, Kronenberg, Mitchell, Ghiasi, Homayon
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258941/
https://ncbi.nlm.nih.gov/pubmed/30282707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01451-18
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