PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance

Engineered oncolytic viruses are used clinically to destroy cancer cells and have the ability to boost anticancer immunity. Phosphatase and tensin homolog deleted on chromosome 10 loss is common across a broad range of malignancies, and is implicated in immune escape. The N-terminally extended isofo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Russell, Luke, Swanner, Jessica, Jaime-Ramirez, Alena Cristina, Wang, Yufeng, Sprague, Alex, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Sizemore, Gina M., Kladney, Raleigh, Zhang, Jianying, Lehman, Norman L., Ostrowski, Michael C, Hong, Bangxing, Caligiuri, Michael, Yu, Jianhua, Kaur, Balveen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258708/
https://ncbi.nlm.nih.gov/pubmed/30479334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07344-1
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