Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9–m...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Tian, Songhai, Muneeruddin, Khaja, Choi, Mei Yuk, Tao, Liang, Bhuiyan, Robiul H., Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Boland, Sebastian, Shaffer, Scott A., Adam, Rosalyn M., Dong, Min
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Methods and Resources
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258472/
https://ncbi.nlm.nih.gov/pubmed/30481169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006951
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