Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9–m...

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Библиографические подробности
Опубликовано в: :PLoS Biol
Главные авторы: Tian, Songhai, Muneeruddin, Khaja, Choi, Mei Yuk, Tao, Liang, Bhuiyan, Robiul H., Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Boland, Sebastian, Shaffer, Scott A., Adam, Rosalyn M., Dong, Min
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2018
Предметы:
Methods and Resources
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258472/
https://ncbi.nlm.nih.gov/pubmed/30481169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006951
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