Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9–m...

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Detalles Bibliográficos
Publicado en:PLoS Biol
Autores principales: Tian, Songhai, Muneeruddin, Khaja, Choi, Mei Yuk, Tao, Liang, Bhuiyan, Robiul H., Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Boland, Sebastian, Shaffer, Scott A., Adam, Rosalyn M., Dong, Min
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
Materias:
Methods and Resources
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258472/
https://ncbi.nlm.nih.gov/pubmed/30481169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006951
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