Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9–m...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Tian, Songhai, Muneeruddin, Khaja, Choi, Mei Yuk, Tao, Liang, Bhuiyan, Robiul H., Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Boland, Sebastian, Shaffer, Scott A., Adam, Rosalyn M., Dong, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258472/
https://ncbi.nlm.nih.gov/pubmed/30481169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006951
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