Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Glycosylation is a fundamental modification of proteins and membrane lipids. Toxins that utilize glycans as their receptors have served as powerful tools to identify key players in glycosylation processes. Here, we carried out Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas9–m...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS Biol
Autori principali: Tian, Songhai, Muneeruddin, Khaja, Choi, Mei Yuk, Tao, Liang, Bhuiyan, Robiul H., Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Boland, Sebastian, Shaffer, Scott A., Adam, Rosalyn M., Dong, Min
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
Soggetti:
Methods and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258472/
https://ncbi.nlm.nih.gov/pubmed/30481169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.2006951
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