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Inhibiting and Remodeling Toxic Amyloid-beta Oligomer Formation Using a Computationally Designed Drug Molecule that Targets Alzheimer’s Disease
Alzheimer’s Disease (AD) is rapidly reaching epidemic status among a burgeoning aging population. Much evidence suggests the toxicity of this amyloid disease is most influenced by the formation of soluble oligomeric forms of Amyloid β-protein, particularly the 42 residue alloform (Aβ42). Developing...
Gorde:
| Argitaratua izan da: | J Am Soc Mass Spectrom |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258352/ https://ncbi.nlm.nih.gov/pubmed/29713966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-018-1975-1 |
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