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Efflux Transporters Regulate Arsenite-Induced Genotoxicity in Double Negative and Double Positive T Cells

Arsenite (As(+3)) exposure is known to cause immunotoxicity in human and animal models. Our previous studies demonstrated that As(+3) at 50–500 nM concentrations induced both genotoxicity and nongenotoxicity in mouse thymus cells. Developing T cells at CD4-CD8- double negative (DN) stage, the first...

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書誌詳細
出版年:Toxicol Sci
主要な著者: Xu, Huan, Medina, Sebastian, Lauer, Fredine T., Douillet, Christelle, Liu, Ke Jian, Hudson, Laurie G., Stýblo, Miroslav, Aleksunes, Lauren M., Burchiel, Scott W.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257016/
https://ncbi.nlm.nih.gov/pubmed/28472378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx075
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