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Environmentally Relevant Concentrations of Arsenite and Monomethylarsonous Acid Inhibit IL-7/STAT5 Cytokine Signaling Pathways in Mouse CD3+CD4−CD8− Double Negative Thymus Cells
Environmental arsenic exposure is a public health issue. Immunotoxicity induced by arsenic has been reported in humans and animal models. The purpose of this study was to evaluate mechanisms of As(+3) and MMA(+3) toxicity in mouse thymus cells. Because we know that MMA(+3) inhibits IL-7 signaling in...
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| Veröffentlicht in: | Toxicol Lett |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4792750/ https://ncbi.nlm.nih.gov/pubmed/26921788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2016.02.014 |
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