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Canonical Wnt/β-catenin signaling activation in soft-tissue sarcomas: A comparative study of synovial sarcoma and leiomyosarcoma

BACKGROUND: Previous studies have shown that aberrant activation of the Wnt/β-catenin pathway is associated with many malignant neoplasms. This includes some soft-tissue sarcoma phenotypes, most notably synovial sarcoma, implicating potential targets for novel molecular therapies. OBJECTIVE: We inve...

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Detalhes bibliográficos
Publicado no:Rare Tumors
Main Authors: Briski, Laurence M, Thomas, Dafydd G, Patel, Rajiv M, Lawlor, Elizabeth R, Chugh, Rashmi, McHugh, Jonathan B, Lucas, David R
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256314/
https://ncbi.nlm.nih.gov/pubmed/30505422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2036361318813431
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