Targeting the Wnt Pathway in Synovial Sarcoma Models

Synovial sarcoma (SS) is an aggressive soft tissue malignancy of children and young adults, with no effective systemic therapies. Its specific oncogene, SYT-SSX (SS18-SSX), drives sarcoma initiation and development. The exact mechanism of SYT-SSX oncogenic function remains unknown. In a SYT-SSX2 tra...

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Detalhes bibliográficos
Main Authors: Barham, Whitney, Frump, Andrea L., Sherrill, Taylor P., Garcia, Christina B., Saito-Diaz, Kenyi, VanSaun, Michael N., Fingleton, Barbara, Gleaves, Linda, Orton, Darren, Capecchi, Mario R., Blackwell, Timothy S., Lee, Ethan, Yull, Fiona, Eid, Josiane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823757/
https://ncbi.nlm.nih.gov/pubmed/23921231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0138
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