Targeting the Wnt Pathway in Synovial Sarcoma Models

Synovial sarcoma (SS) is an aggressive soft tissue malignancy of children and young adults, with no effective systemic therapies. Its specific oncogene, SYT-SSX (SS18-SSX), drives sarcoma initiation and development. The exact mechanism of SYT-SSX oncogenic function remains unknown. In a SYT-SSX2 tra...

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Hlavní autoři: Barham, Whitney, Frump, Andrea L., Sherrill, Taylor P., Garcia, Christina B., Saito-Diaz, Kenyi, VanSaun, Michael N., Fingleton, Barbara, Gleaves, Linda, Orton, Darren, Capecchi, Mario R., Blackwell, Timothy S., Lee, Ethan, Yull, Fiona, Eid, Josiane E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823757/
https://ncbi.nlm.nih.gov/pubmed/23921231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0138
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