Φορτώνει......
Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided
AIMS: We assessed the potential mutual interaction of oral macitentan (cytochrome P450 (CYP) 3A4 substrate) at steady‐state with single‐dose oral rivaroxaban (CYP3A4 and P‐glycoprotein substrate) and evaluated the effect of the CYP3A and P‐glycoprotein inducer St John's wort (SJW) on the pharma...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Br J Clin Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
John Wiley and Sons Inc.
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6255992/ https://ncbi.nlm.nih.gov/pubmed/30192025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13757 |
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