Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury

In toxicogenomics, functional annotation is an important step to gain additional insights into genes with aberrant expression that drive pathophysiological mechanisms. Nevertheless, there exists a gap on annotation of these genes which often hampers the interpretation of results and limits their app...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Souza, Terezinha, Trairatphisan, Panuwat, Piñero, Janet, Furlong, Laura I., Saez-Rodriguez, Julio, Kleinjans, Jos, Jennen, Danyel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255978/
https://ncbi.nlm.nih.gov/pubmed/30515189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00527
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