Dose and Time Dependencies in Stress Pathway Responses during Chemical Exposure: Novel Insights from Gene Regulatory Networks

Perturbation of biological networks is often observed during exposure to xenobiotics, and the identification of disturbed processes, their dynamic traits, and dose–response relationships are some of the current challenges for elucidating the mechanisms determining adverse outcomes. In this scenario,...

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Vydáno v:Front Genet
Hlavní autoři: Souza, Terezinha M., Kleinjans, Jos C. S., Jennen, Danyel G. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649202/
https://ncbi.nlm.nih.gov/pubmed/29085386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00142
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