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Dose and Time Dependencies in Stress Pathway Responses during Chemical Exposure: Novel Insights from Gene Regulatory Networks

Perturbation of biological networks is often observed during exposure to xenobiotics, and the identification of disturbed processes, their dynamic traits, and dose–response relationships are some of the current challenges for elucidating the mechanisms determining adverse outcomes. In this scenario,...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Souza, Terezinha M., Kleinjans, Jos C. S., Jennen, Danyel G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5649202/
https://ncbi.nlm.nih.gov/pubmed/29085386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2017.00142
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