Translational Proteomics Analysis of Anthracycline-Induced Cardiotoxicity From Cardiac Microtissues to Human Heart Biopsies

Anthracyclines, including doxorubicin, idarubicin, and epirubicin, are common antitumor drugs as well as well-known cardiotoxic agents. This study analyzed the proteomics alteration in cardiac tissues caused by these 3 anthracyclines analogs. The in vitro human cardiac microtissues were exposed to d...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Nguyen, Nhan, Souza, Terezinha, Verheijen, Marcha C. T., Gmuender, Hans, Selevsek, Nathalie, Schlapbach, Ralph, Kleinjans, Jos, Jennen, Danyel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239409/
https://ncbi.nlm.nih.gov/pubmed/34211507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.695625
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